Nanocarbon-Coated Porous Anodic Alumina for Bionic Devices
نویسندگان
چکیده
A highly-stable and biocompatible nanoporous electrode is demonstrated herein. The electrode is based on a porous anodic alumina which is conformally coated with an ultra-thin layer of diamond-like carbon. The nanocarbon coating plays an essential role for the chemical stability and biocompatibility of the electrodes; thus, the coated electrodes are ideally suited for biomedical applications. The corrosion resistance of the proposed electrodes was tested under extreme chemical conditions, such as in boiling acidic/alkali environments. The nanostructured morphology and the surface chemistry of the electrodes were maintained after wet/dry chemical corrosion tests. The non-cytotoxicity of the electrodes was tested by standard toxicity tests using mouse fibroblasts and cortical neurons. Furthermore, the cell-electrode interaction of cortical neurons with nanocarbon coated nanoporous anodic alumina was studied in vitro. Cortical neurons were found to attach and spread to the nanocarbon coated electrodes without using additional biomolecules, whilst no cell attachment was observed on the surface of the bare anodic alumina. Neurite growth appeared to be sensitive to nanotopographical features of the electrodes. The proposed electrodes show a great promise for practical applications such as retinal prostheses and bionic implants in general.
منابع مشابه
Engineering optical properties of gold-coated nanoporous anodic alumina for biosensing
The effect in the Fabry-Pérot optical interferences of nanoporous anodic alumina films coated with gold is studied as a function of the porosity and of the gold thickness by means of reflectance spectroscopy. Samples with porosities between 14 and 70% and gold thicknesses (10 and 20 nm) were considered. The sputtering of gold on the nanoporous anodic alumina (NAA) films results in an increase o...
متن کاملSynthesis and Characterization of Silver and Gold Nano-Structures on Chitosan-Porous Anodic Alumina Nano-Composite
This study was designed to probe the fabrication of unique silver and gold nano-structures engaging a self-designed chitosan-porous anodic alumina nano-composite as a template. Porous anodic alumina has been manufactured by di-step aluminum anodization in an oxalic acid electrolytic bath. The surface properties of porous anodic alumina were reinforced by chitosan neutralized in sodium hydro...
متن کاملFabrication of Highly Ordered Gold Nanorods Film Using Alumina Nanopores
A simple method for fabrication of highly ordered gold nanorod film is introduced in this article. The procedure is based on thermal evaporation of gold into a porous anodic alumina film (PAA). The PPA film was fabricated by combining the hard and mild anodization. This combination effectively decreases the processing time of fabrication of highly ordered porous anodic alumina film with c...
متن کاملSelf-supporting nanowire arrays templated in sacrificial branched porous anodic alumina for thermoelectric devices
متن کامل
Ultra-High Density Single Nanometer-Scale Anodic Alumina Nanofibers Fabricated by Pyrophosphoric Acid Anodizing
Anodic oxide fabricated by anodizing has been widely used for nanostructural engineering, but the nanomorphology is limited to only two oxides: anodic barrier and porous oxides. Therefore, the discovery of an additional anodic oxide with a unique nanofeature would expand the applicability of anodizing. Here we demonstrate the fabrication of a third-generation anodic oxide, specifically, anodic ...
متن کامل